Publications
Translational research on cognitive impairment in chronic kidney disease
Authors: Carsten A Wagner, Ziad A Massy, Giovambattista Capasso, Francesco Mattace-Raso, Marion Pepin, Mickaël Bobot, Carmine Zoccali, Ana C Ferreira, Ewout J Hoorn, Pedro H Imenez Silva, Robert J Unwin, Vesna Pesic, CONNECT , Translational research on cognitive impairment in chronic kidney disease, Nephrology Dialysis Transplantation, 2024;, gfae229, AbstractCognitive decline is
Cognitive impairment in CKD patients: a guidance document by the CONNECT network
Authors: Davide Bolignano, Mariadelina Simeoni, Gaye Hafez, Marion Pepin, Antonio Gallo, Manuela Altieri, Sophie Liabeuf, Konstantinos Giannakou, Ananya De, Giovambattista Capasso, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators , Cognitive impairment in CKD patients: a guidance document by the CONNECT network, Clinical Kidney Journal, 2024;, sfae294 AbstractCognitive impairment
Drugs with a negative impact on cognitive functions (Part 3): Antibacterial agents in patients with chronic kidney disease
Authors: Sophie Liabeuf, Gaye Hafez, Vesna Pešić, Goce Spasovski, Mickael Bobot, Romaldas Mačiulaitis, Inga Arune Bumblyte, Ana Carina Ferreira, Ana Farinha, Jolanta Malyszko, Marion Pépin, Ziad A Massy, Robert Unwin, Giovambattista Capasso, Laila-Yasmin Mani Antibacterial agents (ABs) represent a critical component of therapy regimens in patients with CKD due to increased susceptibility to infections. Elucidating AB-induced cognitive effects in patients with CKD demands
Animal models to study cognitive impairment of chronic kidney disease
Pedro H. Imenez Silva*, Marion Pepin*, Andreja Figurek*, Eugenio Gutiérrez-Jiménez, Mickaël Bobot, Anna Iervolino, Francesco Mattace-Raso, Ewout J. Hoorn, Matthew A. Bailey, Lucie Hénaut, Rikke Nielsen, Sebastian Frische, Francesco Trepiccione, Gaye Hafez, Hande O. Altunkaynak, Nicole Endlich, Robert Unwin, Giovambattista Capasso, Vesna Pesic*, Ziad Massy*, Carsten A. Wagner*, and on
Cognitive decline related to chronic kidney disease as an exclusion factor from kidney transplantation: results from an international survey
Authors: Michele Farisco, Inga A Blumblyte, Casper Franssen, Dorothea Nitsch, Irene Zecchino, Giovambattista Capasso, Gaye Hafez, COST CONNECT Action Collaborators View Publication Background and hypothesisThere seems to be a lack of consensus on the necessity and the modality of psychological and specifically cognitive assessment of candidates for kidney transplantation. Both points are often delegated to individual hospitals/centres,
Efficacy of erythropoietin as a neuroprotective agent in CKD-associated cognitive dysfunction: A literature systematic review
Authors: Michelangela Barbieri, Paolo Chiodini, Piergiacomo Di Gennaro, Gaye Hafez, Sophie Liabeuf, Jolanta Malyszko, Laila-Yasmin Mani, Francesco Mattace Raso, Marion Pepin, Norberto Perico, Mariadelina Simeoni, Carmine Zoccali, Giovanni Tortorella, Annalisa Capuano, Giuseppe Remuzzi, Giovambattista Capasso, Giuseppe Paolisso, on behalf of CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators Patients with chronic kidney disease (CKD) often experience mild cognitive impairment and other neurocognitive disorders. Studies have shown that erythropoietin (EPO) and its receptor have neuroprotective effects in cell and animal models of
Drugs with a negative impact on cognitive functions (Part 2): drug classes to consider while prescribing in CKD patients
Authors: Gaye Hafez, Jolanta Malyszko, Aleksandra Golenia, Aleksandra Klimkowicz-Mrowiec, Ana Carina Ferreira, Mustafa Arıcı, Annette Bruchfeld, Dorothea Nitsch, Ziad A Massy, Marion Pépin, Giovambattista Capasso, Laila-Yasmin Mani, Sophie Liabeuf, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) The first review of this series described how CKD could represent a risk factor for adverse drug reactions affecting the central nervous system. This
Drugs with a negative impact on cognitive function (Part 1): chronic kidney disease as a risk factor
Authors: Sophie Liabeuf, Vesna Pešić, Goce Spasovski, Romaldas Maciulaitis, Mickaël Bobot, Ana Farinha, Carsten A Wagner, Robert J Unwin, Giovambattista Capasso, Inga Arune Bumblyte, Gaye Hafez, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) People living with chronic kidney disease (CKD) frequently suffer from mild cognitive impairment and/or other neurocognitive disorders. This review in two parts will focus on
Methodological challenges and biases in the field of cognitive function among patients with chronic kidney disease
Authors: Konstantinos Giannakou, Aleksandra Golenia, Sophie Liabeuf, Jolanta Malyszko, Francesco Mattace-Raso, Ana Farinha, Goce Spasovski, Gaye Hafez, Andrzej Wiecek, Giovanna Capolongo, Giovambattista Capasso, Ziad A. Massy, Marion Pépin on behalf of CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) Download publication here.
Cognitive disorders in patients with chronic kidney disease: Approaches to prevention and treatment
Authors: Marion Pépin, Aleksandra Klimkowicz-Mrowiec , Olivier Godefroy Pilar Delgado , Sol Carriazo, Ana Carina Ferreira , Aleksandra Golenia , Jolanta Malyszko , Tomasz Grodzicki , Konstantinos Giannakou , Giuseppe Paolisso , Michelangela Barbieri , Liliana Garneata , Carmen Antonia Mocanu , Sophie Liabeuf , Goce Spasovski , Carmine Zoccali , Annette Bruchfeld , Ana Farinha , Mustafa Arici, Giovambattista Capasso , Andrzej Wiecek,, Ziad A Massy, CONNECT (Cognitive Decline in Nephro-Neurology: European Cooperative Target) Action Eur J Neurol. 2023 Jun 16. doi: 10.1111/ene.15928Published: 22 December 2022 Download publication here.
The need for a multi-disciplinary reflection about frailty and cognitive impairment in chronic kidney disease
Authors: Michele Farisco, Irene Zecchino, Giovambattista Capasso, CONNECT Consortium Nephrology Dialysis Transplantation, gfac334, https://doi.org/10.1093/ndt/gfac334 Published: 22 December 2022 Download publication: Here
Phosphate in the Context of Cognitive Impairment and Other Neurological Disorders Occurrence in Chronic Kidney Disease
The nervous system and the kidneys are linked under physiological states to maintain normal body homeostasis. In chronic kidney disease (CKD), damaged kidneys can impair the central nervous system, including cerebrovascular disease and cognitive impairment (CI)
Volume 37, Issue Supplement_2, January 2022
CONNECTing the kidney to brain dysfunction: from animal models to clinical practice Sponsored by COST Action CA19127-Cognitive Decline in Nephro-Neurology : European Cooperative Target (CONNECT) https://academic.oup.com/ndt/issue/37/Supplement_2
Brain dysfunction in tubular and tubulointerstitial kidney diseases
Authors: Davide Viggiano, Annette Bruchfeld, Sol Carriazo, Antonio de Donato, Nicole Endlich, Ana Carina Ferreira, Andreja Figurek, Denis Fouque, Casper F M Franssen, Konstantinos Giannakou, Dimitrios Goumenos, Ewout J Hoorn, Dorothea Nitsch, Alberto Ortiz, Vesna Pešić, Daiva Rastenyté, Maria José Soler, Merita Rroji, Francesco Trepiccione, Robert J Unwin, Carsten A Wagner, Andrzej Wieçek, Miriam Zacchia, Carmine Zoccali, Giovambattista Capasso Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_2, January 2022, Pages ii46-i55, https://doi.org/10.1093/ndt/gfab276
Albuminuria as a risk factor for mild cognitive impairment and dementia—what is the evidence?
Authors: Boris Bikbov, Maria José Soler, Vesna Pešić, Giovambattista Capasso, Robert Unwin, Matthias Endres, Giuseppe Remuzzi, Norberto Perico, Ron Gansevoort, Francesco Mattace-Raso, Annette Bruchfeld, Andreja Figurek, Gaye Hafez, the CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) Nephrology Dialysis Transplantation, gfab261, https://doi.org/10.1093/ndt/gfab261 Published: 05 November 2021
Neuropeptide Y as a risk factor for cardiorenal disease and cognitive dysfunction in CKD: translational opportunities and challenges
Authors: Carmine Zoccali, Alberto Ortiz, Inga Arune Blumbyte, Sarina Rudolf, Annette G Beck-Sickinger, Jolanta Malyszko, Goce Spasovski, Sol Carriazo, Davide Viggiano, Justina Kurganaite, Vaiva Sarkeviciene, Daiva Rastenyte, Andreja Figurek, Merita Rroji, Christopher Mayer, Mustapha Arici, Gianvito Martino, Gioacchino Tedeschi, Annette Bruchfeld, Belinda Spoto, Ivan Rychlik, Andrzej Wiecek, Mark Okusa, Giuseppe Remuzzi, Francesca Mallamaci, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) Nephrology Dialysis Transplantation, gfab284, https://doi.org/10.1093/ndt/gfab284 Published: 01 November 2021
Acidosis, cognitive dysfunction and motor impairments in patients with kidney disease
Authors: Pedro H Imenez Silva, Robert Unwin, Ewout J Hoorn, Alberto Ortiz, Francesco Trepiccione, Rikke Nielsen, Vesna Pesic, Gaye Hafez, Denis Fouque, Ziad A Massy, Chris I De Zeeuw, Giovambattista Capasso, Carsten A Wagner, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) Nephrology Dialysis Transplantation, gfab216, https://doi.org/10.1093/ndt/gfab216 Published: 31 October 2021
Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment
Authors: Marion Pépin, Ana Carina Ferreira, Mustafa Arici, Maie Bachman, Michelangela Barbieri, Inga Arune Bumblyte, Sol Carriazo, Pilar Delgado, Liliana Garneata, Konstantinos Giannakou, Olivier Godefroy, Tomasz Grodzicki, Aleksandra Klimkowicz-Mrowiec, Justina Kurganaite, Sophie Liabeuf, Carmen Antonia Mocanu, Giuseppe Paolisso, Goce Spasovski, Evgueniy Stefanov Vazelov, Davide Viggiano, Carmine Zoccali, Ziad A Massy, Andrzej Więcek, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) Nephrology Dialysis Transplantation, gfab262, https://doi.org/10.1093/ndt/gfab262 Published: 31 October 2021
Chronic kidney disease and neurological disorders: are uraemic toxins the missing piece of the puzzle?
Authors: Sophie Liabeuf, Marion Pepin, Casper F M Franssen, Davide Viggiano, Sol Carriazo, Ron T Gansevoort, Loreto Gesualdo, Gaye Hafez, Jolanta Malyszko, Christopher Mayer, Dorothea Nitsch, Alberto Ortiz, Vesna Pešić, Andrzej Wiecek, Ziad A Massy, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) Nephrology Dialysis Transplantation, gfab223, https://doi.org/10.1093/ndt/gfab223 Published: 31 October 2021
